Husik I was a 4th-century Armenian patriarch belonging to the hereditary Gregorid line. As the grandson of Gregory the Illuminator and son of Vrtanes I, he served as the Catholicos of All Armenians from 341 to 347 during the reign of King Tiran. His leadership was marked by significant tension with the monarchy, stemming from religious or political disagreements. This conflict ultimately led to his violent death at the hands of the king's associates, ending his brief tenure as the head of the Armenian Church.