Constantius of Perugia was a 2nd-century Christian bishop who served as the first leader of the church in Perugia. According to local tradition, he assumed his episcopal role at the age of thirty, dedicating his ministry to evangelism and assisting those in poverty. He lived during a period of Roman persecutions, which eventually led to his death near Foligno after he was arrested and tortured in the prisons of Assisi and Spello.