Possidius of Calama was a 5th-century bishop in the Roman province of Numidia and a close companion of Augustine of Hippo. Maintaining a friendship with Augustine for forty years, he served as a member of the clergy within Augustine's monastery. He eventually rose to the episcopate, likely around 397, and established a monastery in Calama. Throughout his career, he navigated intense religious conflicts involving Donatists and pagans, eventually fleeing to Hippo during the Vandal invasion before dying in Apulia.