John Dominici was a 14th-century Italian Dominican prelate and theologian who served as a cardinal and archbishop. Born in Florence, he initially faced challenges entering his religious order due to a speech impairment, a condition he reportedly overcame through prayer. He became a highly influential preacher and scholar, eventually serving as a papal legate and a key figure during the Council of Constance. His theological insights left a lasting impact on religious art, particularly influencing the work of the painter Fra Angelico.