Ignacia del Espíritu Santo was a 17th-century Filipino religious sister who established the first congregation for native women in the Philippines. Born in Binondo around 1663, she sought a life of religious devotion despite colonial restrictions that barred local women from existing religious houses. Following spiritual guidance from a Jesuit priest, she founded the Religious of the Virgin Mary, a community that supported itself through manual labor. Recognized for her piety and poverty, she was declared venerable by the Catholic Church in 2007.