Domnina of Terni was a Christian martyr who lived during the middle of the third century. According to historical tradition, she resided in Terni and suffered martyrdom alongside ten consecrated virgins. Her death is said to have occurred simultaneously with the execution of Saint Valentine, the bishop of Terni. While some sources suggest her death might have taken place during the sixth-century reign of Totila, she is traditionally associated with the earlier period of Roman persecution.