Cuthbert Mayne was a 16th-century English Catholic priest who became the first martyr among those trained at the English College in Douai. Born near Barnstaple, he studied at Oxford before traveling to the Continent for religious training. Following his ordination in 1575, he returned to England to serve the Catholic mission. His religious activities led to his arrest at Golden Manor, resulting in a charge of high treason under the reign of Elizabeth I.