Constantina was the eldest daughter of the Roman emperor Constantine the Great and his wife Fausta. Born in Rome around 315, she lived a life deeply intertwined with the political shifts of the early Roman Empire. She was married twice, first to her cousin Hannibalianus and later to the Caesar Constantius Gallus. Following the death of her father, she navigated complex imperial power struggles, eventually moving to Antioch to govern with her second husband. She died in 354 in Bithynia while traveling to meet her brother, Constantius II.