Gennadius of Constantinople was a 5th-century prelate who served as the Ecumenical Patriarch of Constantinople from 458 until his death in 471. Originally from Antioch, he was a highly educated writer who utilized the literal exegetical methods associated with the School of Antioch. During his tenure, he was noted for his administrative skills and his commitment to maintaining ecclesiastical discipline. He played a significant role in addressing issues such as simony and managing religious tensions within the Byzantine Empire, including interactions with the monophysite movement.