Serapion of Novgorod was an Eastern Orthodox prelate who served as the Archbishop of Novgorod the Great and Pskov between 1506 and 1509. Born in the Muscovite village of Pekhorka, he rose through monastic ranks, serving as hegumen of the Dubensk Dormition, Stromyn Dormition, and Trinity monasteries. His tenure as archbishop was brief, ending after a conflict with Joseph Volotsky and the Grand Prince Vasily III, which resulted in his removal from office.