Meletius of Antioch was a 4th-century Christian patriarch who led the see of Antioch from 360 until 381. Born into a wealthy family in Melitene, he initially served as the bishop of Sebaste. His leadership was defined by the Meletian schism, a period of intense division within the church. Despite facing multiple exiles due to shifting imperial religious policies, he eventually emerged as a leader of orthodoxy. He concluded his career by presiding over the First Council of Constantinople, a major ecumenical gathering.