Trophimus was a Christian from Ephesus who traveled alongside the apostle Paul during his third missionary journey. As one of the companions from Asia, he accompanied Paul through Macedonia and into Asia before arriving in Jerusalem. While in Jerusalem, a crowd mistakenly believed Paul had brought him into the temple, an event that triggered a riot and led to Paul's subsequent arrest by Roman authorities. Later, Paul noted that he had left Trophimus in Miletus due to an illness.