Maria Josefa Karolina Brader was a Swiss religious sister born in 1860 who dedicated her life to missionary work in South America. After entering a Franciscan convent in Altstätten, she volunteered for missions in Ecuador, where she served as a teacher and catechist. In 1893, she established the Franciscan Sisters of Mary Immaculate to train more missionaries. She spent much of her later life in Colombia, working with the poor, before passing away in 1943. She is recognized as a saint in the Catholic tradition.