Maria Domenica Mantovani was an Italian nun born in 1862 who co-founded the Little Sisters of the Holy Family alongside Giuseppe Nascimbeni. Following her religious vocation, she served as the first superior of her congregation for forty years. She lived much of her life in the Verona region, specifically in Brenzone sul Garda, where she eventually passed away in 1934. Recognized for her devotion to the poor and her commitment to the Holy Family, she was later canonized by the Catholic Church.