Pope Macarius II of Alexandria was the 69th Pope of the Coptic Orthodox Church, serving as the Patriarch of the See of St. Mark. Born in Egypt around 1050, he originally lived as a monk at the Monastery of Saint Macarius. After practicing asceticism in the desert, he was ordained a priest. He was later selected by bishops in the Scetes wilderness to lead the church, an appointment he accepted reluctantly. He held the papal throne for twenty-seven years until his death in 1128.