Alexios V Megas Komnenos was a young Trapezuntine ruler who briefly held the throne in 1460. Born in 1454 to the co-emperor Alexander, he was designated as the heir to his uncle, John IV. However, his reign lasted only a short time before he was deposed by another uncle, David, who seized power with aristocratic support. Following the Ottoman conquest of Trebizond, Alexios was eventually executed in Constantinople in 1463 alongside members of his family.