Safta Brâncoveanu (1776–1857) was a Romanian noble and philanthropist known for her extensive charitable works. Born in Balș, she married Grigore Brâncoveanu, the lord of Craiova, in 1793. Following her husband's death in 1832, she moved to the Văratec Monastery with her mother, eventually entering the monastic life in 1840. Her life was defined by significant contributions to religious and social welfare, including the establishment of medical facilities for those in need.