Macarius of Ghent was an Armenian bishop who lived from approximately 901 until 1012. Originally from Armenia, he served as the bishop of Antioch toward the end of the 10th century. He eventually abandoned his position, leaving the diocese to a vicar, to undertake a pilgrimage to Jerusalem. After surviving an assassination attempt by attackers in the Holy Land, he traveled to Europe, eventually settling in Ghent, Flanders, in 1011. He died there in 1012 after falling ill with the plague.