Sisoes the Great was an early Christian desert father and ascetic monk who lived in Egypt during the 4th and 5th centuries. Born in Egypt, he sought a life of solitude and withdrew from society during his youth. After initially studying under the guidance of Abba Or, he eventually moved across the Nile to Mount Colzim. There, he inhabited a cave previously used by Anthony the Great to further his pursuit of a secluded, ascetic lifestyle.