Natalia of Nicomedia was a Christian martyr who lived during the early fourth century in the Roman Empire. She was the wife of Adrian, a high-ranking official in Nicomedia who converted to Christianity. After her husband publicly declared his faith and was imprisoned, Natalia reportedly visited him in disguise to request his prayers. She remained present during his execution and is remembered alongside him for her devotion to her faith during the reign of Emperor Maximian.