Isaac of Armenia was a 4th-century Armenian Catholicos who served as the head of the Armenian Church from approximately 387 until 438. A descendant of Gregory the Illuminator, he was the final patriarch of the Gregorid line. He played a vital role in preserving Armenian culture by supporting Mesrop Mashtots in the development of the Armenian alphabet. Beyond his linguistic contributions, he was a scholar of philosophy and rhetoric who actively participated in translating the Bible into the Armenian language.