Doamna Despina Milița was a 16th-century princess of Wallachia who served as regent for her son, Teodosie, between 1521 and 1522. Born around 1487, she was of Serbian noble descent, potentially linked to the Branković or Lazarević families. After her marriage to Neagoe Basarab, she eventually entered a monastery, where she lived under the name Platonida. She died in Sibiu in 1554 and is recognized as a saint within the Orthodox tradition.