Lupus of Sens was a 7th-century bishop who served as the nineteenth leader of the see of Sens. Born in the Orléanais region to Betton, the Count of Tonnerre, he was a member of the royal house of Burgundy. During his tenure, he was noted for his ability to navigate the political tensions between the competing Merovingian princes, demonstrating both firmness and tact in his diplomatic dealings.