Flavian II of Antioch was a 5th-century presbyter and hierarch who served as the Patriarch of Antioch from 498 until 512. Originally a monk following the rule of St. Basil, he was appointed to the patriarchate by Emperor Anastasius I. During his leadership, he navigated intense theological conflicts by attempting to find a middle ground between Chalcedonian and non-Chalcedonian factions. His efforts to maintain peace eventually led to his deposition and exile, which contributed to political unrest within the empire.